Best Excel Python Library (List For Developers)

Updated June 6, 2024

In the diverse environment of Python programming, manipulating and writing data to Microsoft Excel files is a common requirement for data analysis, reporting, and automation tasks. With several Python packages available, including Pandas, OpenPyXL, and IronXL, selecting the right library for the job can be daunting.

In this comprehensive guide, we'll explore the strengths, weaknesses, and key considerations of the Python packages mentioned above to help you make an informed decision based on your specific requirements.

1. Pandas: The Data Analysis Powerhouse

Pandas is widely recognized as one of the go-to open-source Python libraries for data manipulation and analysis in Python. It provides powerful data structures like DataFrames and Series, along with a plethora of functions for data cleaning, transformation, and visualization.

Best Excel Python Library (List For Developers): Figure 1 - Pandas


The following features of Pandas make it a powerful library:

  • Stellar analysis, data manipulation, and visualization capabilities.
  • Efficiently handles large datasets with optimized performance.
  • Integrates seamlessly with NumPy for numerical computations and statistical analysis.
  • Reads and writes various file formats, including Microsoft Excel files (.XLSX).
  • Excellent for cleaning, transforming, and preparing data for further analysis.


  • Limited control over Excel formatting (fonts, styles, charts).
  • Not ideal for complex spreadsheet interactions or automation tasks beyond basic data manipulation.

2. OpenPyXL: The Versatile Read/Write Champion

OpenPyXL is a dedicated Python library for reading and writing Excel files. It excels in preserving data integrity and formatting while providing an extensive API for creating and manipulating Excel files. Active maintenance and a focus on Excel file structure make OpenPyXL a reliable choice for projects involving complex Excel file manipulations.

Best Excel Python Library (List For Developers): Figure 2 - OpenPyXL- read Excel files


Here are some key features of OpenPyXL that make it stand out among others:

  • Reads and writes modern Excel files (.XLSX, .XLSM, .XLTX, .XLTM) with ease.
  • Maintains data integrity and formatting, including conditional formatting and charts.
  • Extensive API for creating new Excel files, manipulating existing ones, and performing advanced operations.


  • Less emphasis on data analysis compared to Pandas, which is more focused on read/write operations.
  • Can be slower for very large datasets, especially compared to specialized data analysis libraries like Pandas.

3. IronXL: The Ultimate Python Excel Library

IronXL is a robust and feature-rich Python library specifically designed for Excel automation tasks. With its comprehensive set of functionalities, IronXL empowers developers to create, read, write, modify, and format Excel files seamlessly within their Python projects. What sets IronXL apart is its focus on advanced Excel automation, offering support for complex tasks such as macros, formulas, and intricate formatting controls.

Best Excel Python Library (List For Developers): Figure 3 - IronXL

Its intuitive API and Excel-like object model make it easy to integrate and work with, while its cross-platform compatibility ensures flexibility across various operating systems and cloud platforms. Whether it's generating detailed reports, performing data analysis, or building sophisticated Excel-based workflows, IronXL provides the tools and capabilities needed to streamline Excel-related tasks efficiently.

The following simple Python code demonstrates how easy it is to integrate IronXL in Python projects and read Excel files using it:

from ironxl import *      
# Supported for XLSX, XLS, XLSM, XLTX, CSV, and TSV
# Load Existing File (Excel Workbook)
workbook = WorkBook.Load("sample.xlsx")
# Select worksheet at index 0
worksheet = workbook.WorkSheets[0]
# Get any existing worksheet
first_sheet = workbook.DefaultWorkSheet
# Select a cell and return the converted value
cell_value = worksheet["A2"].IntValue
# Read from ranges of cells elegantly.
for cell in worksheet["A2:A10"]:
    print("Cell {} has value '{}'".format(cell.AddressString, cell.Text))
# Calculate aggregate values such as Min, and Sum
total_sum = worksheet["A2:A10"].Sum()

For more Excel operations like create and write Excel files, filter existing Excel Files, and convert to XLSX file from other formats, please visit this ready-to-use Python scripts on the code examples page.


Here are some key strengths of IronXL:

  • Feature-rich for advanced Excel automation tasks, suitable for complex workflows.
  • Supports various Excel interactions, writing data including macros, formulas, and charts.
  • Handles complex formatting and chart creation with ease.
  • Offers an Excel-like object model for intuitive use and seamless integration.


  • Requires a commercial license for use, which may not be suitable for open-source projects or budget constraints.
  • Limited community support compared to free and open-source alternatives like Pandas and OpenPyXL.

Key Considerations for Selection

Primary Task: Identify your primary task—data analysis (Pandas), read/write operations with formatting (OpenPyXL), or in-depth Excel automation (IronXL).

Data Volume: Consider the size of your datasets—Pandas excels with performance for massive datasets, while OpenPyXL and IronXL may offer better file size management.

Formatting Requirements: If intricate formatting control is crucial, prioritize OpenPyXL and IronXL over Pandas.

Cost: Pandas and OpenPyXL are free and open-source, while IronXL requires a commercial license.

When to Use Each Library?


Here are some key points to consider when using Pandas:

  • Data cleaning, transformation, and analysis.
  • Exploratory data analysis (EDA).
  • Preparing data for machine learning models.


Here are some key points to consider when using OpenPyXL:

  • Reading and writing modern Excel files with formatting preservation.
  • Creating new Excel reports from scratch.
  • Modifying existing Excel files with detailed control over elements.


Here are some key points to consider when using IronXL:

  • Advanced Excel automation tasks requiring extensive functionality.
  • Interacting with Excel features like macros, formulas, and charts.
  • Building complex Excel-based workflows and applications.

Additional Considerations

Community and Documentation

Pandas and OpenPyXL have extensive communities and documentation. IronXL not only has extensive community and documentation but it also provides ready-use code examples to ease the process of working with Excel data.


Pandas can seamlessly work with OpenPyXL for data-centric workflows, and IronXL can interact with other Excel-related Python packages or libraries for comprehensive solutions.


The following comparison table shows an overview of the discussed libraries:

Best Excel Python Library (List For Developers): Figure 4 - Comparison

In conclusion, selecting the best Excel Python library depends on your specific requirements, including data analysis needs, formatting control, and automation tasks. By considering the strengths, weaknesses, and key considerations outlined in this guide, you can confidently choose the most suitable Python Package for your Excel manipulation tasks.

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